STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tkt1Tkt1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (667 aa)    
Predicted Functional Partners:
talC
TalC; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 0.994
rpe
Rpe; Ribulose-phosphate 3-epimerase Rpe (pentose-5-phosphate 3-epimerase).
 0.986
pgi
Pgi; Glucose-6-phosphate isomerase Pgi (GPI) (phosphoglucose isomerase) (PGI) (phosphohexose isomerase) (PHI); Belongs to the GPI family.
 
 0.983
glpX
GlpX; Fructose-1,6-bisphosphatase GlpX (D-fructose-1,6-bisphosphate 1-phosphohydrolase class II) (FBPase II).
   
 0.979
fba2
Fba2; Fructose-bisphosphate aldolase Fba.
  
 
 0.954
eno
Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.954
ACN16634.1
Putative ketose-bisphosphate aldolase family protein.
  
 
 0.954
pyk
Pyk; Pyruvate kinase (PK); Belongs to the pyruvate kinase family.
  
 0.950
prsA1
PrsA1; Ribose-phosphate pyrophosphokinase PrsA.
   
 
 0.948
prsA2
PrsA2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 
 0.948
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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