STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflD2PflD2; Formate C-acetyltransferase PflD2 (Pyruvate formate-lyase 2) PflD2. (786 aa)    
Predicted Functional Partners:
pflC2
PflC2; Pyruvate formate-lyase, activating enzyme PflC2.
  
 0.975
putA2
PutA2; NAD-dependent aldehyde dehydrogenase PutA; Belongs to the aldehyde dehydrogenase family.
 
 
 0.934
pflC1
PflC1; Pyruvate formate-lyase, activating enzyme PflC1.
  
 0.928
proC
ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
 0.911
pflD1
PflD1; Formate C-acetyltransferase PflD1 (Pyruvate formate-lyase 1).
  
  
 
0.903
putA1
PutA1; Bifunctional protein PutA [Includes: Proline dehydrogenase; P5C dehydrogenase].
     
 0.900
porA4
PorA4; Pyruvate:ferredoxin oxidoreductase, subunit PorA4.
     
 0.664
ACN13979.1
Zn-dependent dehydrogenase.
  
  
 0.652
ogt
Ogt; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.616
ACN17984.1
Conserved hypothetical protein.
       0.616
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.