STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAProbable hydrogenase accessory protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (115 aa)    
Predicted Functional Partners:
hypB
Probable hydrogenase accessory protein HypB.
 
 
 0.966
hypE
Probable hydrogenase accessory protein HypE.
 
  
 0.906
hynD
Probable hydrogenase maturation endopeptidase.
 
  
 0.902
hynA
Probable Ni/Fe-hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.876
hypF
Probable hydrogenase accessory protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.861
hypD
Probable hydrogenase accessory protein HypD; Belongs to the HypD family.
 
  
 0.861
hynC
Probable Ni/Fe-hydrogenase, cytochrome subunit.
 
   
 0.859
hypC
Probable hydrogenase accessory protein HypC.
 
  
 0.859
hynB
Probable Ni/Fe-hydrogenase, small subunit.
 
  
 0.739
DP0159
Related to cytochrome-c3 hydrogenase (NiFeSe), large subunit.
 
 
 0.684
Your Current Organism:
Desulfotalea psychrophila
NCBI taxonomy Id: 177439
Other names: D. psychrophila LSv54, Desulfotalea psychrophila LSv54
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