STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkAProbable 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (361 aa)    
Predicted Functional Partners:
DP3116
Probable pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.999
pgi
Probable glucose-6-phosphate isomerase.
  
 0.990
guaA
Probable GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
   
  
 0.958
DP2717
Related to fructose-bisphosphate aldolase.
  
 
 0.952
DP1665
Related to glycerol-inducible protein; Belongs to the FBPase class 2 family.
  
 
 0.938
fbp
Related to fructose-1,6-bisphosphatase.
  
  
 0.937
tal
Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.931
DP2457
Probable fructose-1,6-bisphosphate aldolase.
    
 0.927
DP2458
Related to mannose-6-phosphate isomerase.
    
 0.919
eno
Probable enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.900
Your Current Organism:
Desulfotalea psychrophila
NCBI taxonomy Id: 177439
Other names: D. psychrophila LSv54, Desulfotalea psychrophila LSv54
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