STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DP1957Probable 3-isopropylmalate dehydratase, large subunit; Belongs to the aconitase/IPM isomerase family. (427 aa)    
Predicted Functional Partners:
leuB
Probable 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
 0.999
DP1958
Related to 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family.
 
 0.999
DP0660
Probable 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.988
leuA
Probable 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
 
 
 0.982
DP0894
Probable dihydroxy-acid dehydratase.
 
  
 0.912
DP2770
Probable acetolactate synthase, small subunit.
 
  
 0.904
DP0895
Probable dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.895
pfor
Probable pyruvate-flavodoxin oxidoreductase.
  
 0.861
DP0726
Probable ketol-acid reductoisomerase.
 
  
 0.848
DP0727
Probable ketol-acid reductoisomerase.
  
  
 0.827
Your Current Organism:
Desulfotalea psychrophila
NCBI taxonomy Id: 177439
Other names: D. psychrophila LSv54, Desulfotalea psychrophila LSv54
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.