STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DP2503Probable RNA polymerase sigma factor (RpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (447 aa)    
Predicted Functional Partners:
dnaG
Related to DNA primase (DnaG); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.881
rpoA
Probable DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.868
rpoB
Probable DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.867
DP0195
Related to transcriptional regulator of multidrug-efflux transporter genes.
  
 
 0.847
DP1820
Related to multidrug-efflux transporter regulator.
  
 
 0.847
rpoZ
Probable DNA-directed RNA polymerase, omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.816
rpoC
Probable DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.801
nusA
Related to transcription termination factor (NusA); Participates in both transcription termination and antitermination.
 
 
 0.766
DP2731
Related to transcription factor.
   
 
 0.693
secD
Related to protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
   
 0.664
Your Current Organism:
Desulfotalea psychrophila
NCBI taxonomy Id: 177439
Other names: D. psychrophila LSv54, Desulfotalea psychrophila LSv54
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