STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leuAProbable 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (565 aa)    
Predicted Functional Partners:
DP1957
Probable 3-isopropylmalate dehydratase, large subunit; Belongs to the aconitase/IPM isomerase family.
 
 
 0.982
DP1958
Related to 3-isopropylmalate dehydratase, small subunit; Belongs to the LeuD family.
  
 
 0.981
DP0192
Probable branched-chain amino acid aminotransferase.
  
 0.975
DP0894
Probable dihydroxy-acid dehydratase.
  
 
 0.961
DP0895
Probable dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.961
DP0085
Related to D-alanine aminotransferase.
 
 0.957
DP2770
Probable acetolactate synthase, small subunit.
 
 
 0.952
pfor
Probable pyruvate-flavodoxin oxidoreductase.
  
 
 0.950
DP0892
Related to 2-oxoglutarate synthase, subunit KorA.
  
 
 0.922
oforA
Probable 2-oxoacid ferredoxin oxidoreductase, alpha subunit.
  
 
 0.922
Your Current Organism:
Desulfotalea psychrophila
NCBI taxonomy Id: 177439
Other names: D. psychrophila LSv54, Desulfotalea psychrophila LSv54
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