STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (491 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 0.999
purA
Hypothetical protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.974
OPL18923.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.965
purH
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.953
OPL19498.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.944
OPL18380.1
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.932
OPL18982.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily.
  
 
 0.923
htpG
Hypothetical protein; Molecular chaperone. Has ATPase activity.
   
 0.912
OPL18128.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.902
OPL18883.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.885
Your Current Organism:
Aegiribacteria bacterium MLSC
NCBI taxonomy Id: 1775674
Other names: C. Aegiribacteria bacterium MLS_C, Candidatus Aegiribacteria bacterium MLS_C, bacterium MLS_C
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