STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPL19604.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.936
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.741
OPL18923.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.649
apt
Hypothetical protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.619
OPL19826.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.593
OPL19496.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.582
purH
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.577
AVO35_09825
Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.574
purA
Hypothetical protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.550
OPL19605.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
Your Current Organism:
Aegiribacteria bacterium MLSC
NCBI taxonomy Id: 1775674
Other names: C. Aegiribacteria bacterium MLS_C, Candidatus Aegiribacteria bacterium MLS_C, bacterium MLS_C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.