| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KUO41753.1 | KUO41755.1 | APZ16_00305 | APZ16_00315 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.645 |
| KUO41753.1 | KUO41757.1 | APZ16_00305 | APZ16_00325 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0215 family. | 0.595 |
| KUO41753.1 | KUO41758.1 | APZ16_00305 | APZ16_00330 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.584 |
| KUO41753.1 | KUO41759.1 | APZ16_00305 | APZ16_00340 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.710 |
| KUO41753.1 | KUO41760.1 | APZ16_00305 | APZ16_00345 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.510 |
| KUO41753.1 | KUO41781.1 | APZ16_00305 | APZ16_00335 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.563 |
| KUO41753.1 | csl4 | APZ16_00305 | APZ16_00310 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.740 |
| KUO41753.1 | pcn | APZ16_00305 | APZ16_00350 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.689 |
| KUO41753.1 | priL | APZ16_00305 | APZ16_00355 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.422 |
| KUO41753.1 | rpoL | APZ16_00305 | APZ16_00320 | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.698 |
| KUO41755.1 | KUO41753.1 | APZ16_00315 | APZ16_00305 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.645 |
| KUO41755.1 | KUO41757.1 | APZ16_00315 | APZ16_00325 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0215 family. | 0.613 |
| KUO41755.1 | KUO41758.1 | APZ16_00315 | APZ16_00330 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.613 |
| KUO41755.1 | KUO41759.1 | APZ16_00315 | APZ16_00340 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.613 |
| KUO41755.1 | KUO41760.1 | APZ16_00315 | APZ16_00345 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.605 |
| KUO41755.1 | KUO41781.1 | APZ16_00315 | APZ16_00335 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.613 |
| KUO41755.1 | csl4 | APZ16_00315 | APZ16_00310 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.773 |
| KUO41755.1 | pcn | APZ16_00315 | APZ16_00350 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.605 |
| KUO41755.1 | priL | APZ16_00315 | APZ16_00355 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.481 |
| KUO41755.1 | rpoL | APZ16_00315 | APZ16_00320 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.686 |