STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APZ16_00585Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)    
Predicted Functional Partners:
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.931
KUO42638.1
Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.813
KUO40226.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.808
KUO40931.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.765
KUO39685.1
S-adenosylmethionine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.765
KUO39413.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
 0.722
KUO40161.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.689
gcvPB
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
  
 
 0.655
KUO41443.1
3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.626
gcvT
Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine.
    
 0.617
Your Current Organism:
Hadesarchaea archaeon
NCBI taxonomy Id: 1776334
Other names: H. archaeon YNP_45, Hadesarchaea archaeon YNP_45
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.