STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (316 aa)    
Predicted Functional Partners:
KUO39834.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.926
pcn
Hypothetical protein; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
 0.861
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
  
 0.814
KUO42443.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.751
KUO39833.1
3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HMG-CoA reductase family.
   
   0.750
KUO40398.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.750
KUO39909.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.739
KUO42437.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.736
KUO40130.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.736
top6A
DNA topoisomerase VI; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
    
 0.714
Your Current Organism:
Hadesarchaea archaeon
NCBI taxonomy Id: 1776334
Other names: H. archaeon YNP_45, Hadesarchaea archaeon YNP_45
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