STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIHypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (376 aa)    
Predicted Functional Partners:
KUO42490.1
Cysteine desulfurase NifS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.800
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 0.800
KUO42573.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.774
KUO42440.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.660
KUO40697.1
Adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.589
KUO42574.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.566
pdxS
Pyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
     
 0.526
APZ16_01025
Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.525
KUO42575.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.518
KUO42571.1
Flavodoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.508
Your Current Organism:
Hadesarchaea archaeon
NCBI taxonomy Id: 1776334
Other names: H. archaeon YNP_45, Hadesarchaea archaeon YNP_45
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