STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (174 aa)    
Predicted Functional Partners:
KUO42441.1
Hypothetical protein; Purine nucleoside phosphorylase involved in purine salvage.
 
 
 0.991
guaA
Hypothetical protein; Catalyzes the synthesis of GMP from XMP.
  
 0.986
KUO39296.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.831
ade
Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
   
 0.811
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 
 0.807
KUO39987.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.779
KUO40875.1
Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.737
tuf-2
ADSL_C domain-containing protein; Metagenomic; derived from metagenome: hot springs metagenome.
  
 0.737
KUO40776.1
Hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
   
 
  0.718
KUO40009.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.711
Your Current Organism:
Hadesarchaea archaeon
NCBI taxonomy Id: 1776334
Other names: H. archaeon YNP_45, Hadesarchaea archaeon YNP_45
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