STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORV60015.1Uracil phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPRTase family. (207 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.976
ORV71050.1
Pyrimidine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.975
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.953
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.952
guaA
Transcriptional regulator; Catalyzes the synthesis of GMP from XMP.
  
  
 0.938
ORV60014.1
Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.911
cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.895
ORV64460.1
Ribose-5-phosphate isomerase; Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.883
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
   
 
 0.872
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.839
Your Current Organism:
Mycobacterium gastri
NCBI taxonomy Id: 1777
Other names: ATCC 15754, CCUG 20995, CIP 104530, DSM 43505, JCM 12407, M. gastri
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