STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORV74587.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (571 aa)    
Predicted Functional Partners:
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
   
 0.946
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.939
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.920
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
  0.894
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.891
ORV76650.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.868
ORV80142.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.857
ORV65551.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.852
ORV74237.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.852
ORV67369.1
Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.843
Your Current Organism:
Mycobacterium gastri
NCBI taxonomy Id: 1777
Other names: ATCC 15754, CCUG 20995, CIP 104530, DSM 43505, JCM 12407, M. gastri
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.