node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SAK42315.1 | SAK44596.1 | AWB77_00439 | AWB77_00731 | Class IV aminotransferase. | Para-aminobenzoate synthase subunit I. | 0.700 |
SAK42315.1 | SAK49456.1 | AWB77_00439 | AWB77_01133 | Class IV aminotransferase. | Isopropylmalate isomerase large subunit. | 0.699 |
SAK42315.1 | SAK52011.1 | AWB77_00439 | AWB77_01357 | Class IV aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.819 |
SAK42315.1 | SAK81006.1 | AWB77_00439 | AWB77_04023 | Class IV aminotransferase. | Acetolactate synthase 3 catalytic subunit. | 0.557 |
SAK42315.1 | SAL01515.1 | AWB77_00439 | AWB77_06353 | Class IV aminotransferase. | Glutamate synthase. | 0.499 |
SAK42315.1 | ilvC | AWB77_00439 | AWB77_04021 | Class IV aminotransferase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.493 |
SAK42315.1 | ilvE | AWB77_00439 | AWB77_00813 | Class IV aminotransferase. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.662 |
SAK42315.1 | leuA | AWB77_00439 | AWB77_00574 | Class IV aminotransferase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.828 |
SAK42315.1 | leuA-2 | AWB77_00439 | AWB77_03951 | Class IV aminotransferase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.828 |
SAK44596.1 | SAK42315.1 | AWB77_00731 | AWB77_00439 | Para-aminobenzoate synthase subunit I. | Class IV aminotransferase. | 0.700 |
SAK44596.1 | SAK49456.1 | AWB77_00731 | AWB77_01133 | Para-aminobenzoate synthase subunit I. | Isopropylmalate isomerase large subunit. | 0.778 |
SAK44596.1 | SAK52011.1 | AWB77_00731 | AWB77_01357 | Para-aminobenzoate synthase subunit I. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.812 |
SAK44596.1 | SAK81006.1 | AWB77_00731 | AWB77_04023 | Para-aminobenzoate synthase subunit I. | Acetolactate synthase 3 catalytic subunit. | 0.719 |
SAK44596.1 | SAL01515.1 | AWB77_00731 | AWB77_06353 | Para-aminobenzoate synthase subunit I. | Glutamate synthase. | 0.631 |
SAK44596.1 | ilvC | AWB77_00731 | AWB77_04021 | Para-aminobenzoate synthase subunit I. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.763 |
SAK44596.1 | ilvE | AWB77_00731 | AWB77_00813 | Para-aminobenzoate synthase subunit I. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.631 |
SAK44596.1 | leuA | AWB77_00731 | AWB77_00574 | Para-aminobenzoate synthase subunit I. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.816 |
SAK44596.1 | leuA-2 | AWB77_00731 | AWB77_03951 | Para-aminobenzoate synthase subunit I. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.816 |
SAK49456.1 | SAK42315.1 | AWB77_01133 | AWB77_00439 | Isopropylmalate isomerase large subunit. | Class IV aminotransferase. | 0.699 |
SAK49456.1 | SAK44596.1 | AWB77_01133 | AWB77_00731 | Isopropylmalate isomerase large subunit. | Para-aminobenzoate synthase subunit I. | 0.778 |