node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OBJ77442.1 | OBJ77699.1 | A9W97_05310 | A9W97_00495 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
OBJ77442.1 | OBJ85752.1 | A9W97_05310 | A9W97_19125 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.893 |
OBJ77442.1 | OBJ89729.1 | A9W97_05310 | A9W97_14070 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.893 |
OBJ77442.1 | OBJ91304.1 | A9W97_05310 | A9W97_01005 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. | 0.898 |
OBJ77442.1 | ilvC | A9W97_05310 | A9W97_00500 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.883 |
OBJ77442.1 | ilvD | A9W97_05310 | A9W97_06085 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.671 |
OBJ77442.1 | leuA | A9W97_05310 | A9W97_27115 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.906 |
OBJ77442.1 | leuC | A9W97_05310 | A9W97_00560 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.925 |
OBJ77442.1 | leuD | A9W97_05310 | A9W97_00565 | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.936 |
OBJ77699.1 | OBJ77442.1 | A9W97_00495 | A9W97_05310 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
OBJ77699.1 | OBJ85752.1 | A9W97_00495 | A9W97_19125 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
OBJ77699.1 | OBJ89729.1 | A9W97_00495 | A9W97_14070 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.892 |
OBJ77699.1 | ilvC | A9W97_00495 | A9W97_00500 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
OBJ77699.1 | ilvD | A9W97_00495 | A9W97_06085 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.969 |
OBJ77699.1 | leuA | A9W97_00495 | A9W97_27115 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.978 |
OBJ77699.1 | leuC | A9W97_00495 | A9W97_00560 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.896 |
OBJ77699.1 | leuD | A9W97_00495 | A9W97_00565 | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.947 |
OBJ77708.1 | leuC | A9W97_00555 | A9W97_00560 | IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.978 |
OBJ77708.1 | leuD | A9W97_00555 | A9W97_00565 | IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.949 |
OBJ85752.1 | OBJ77442.1 | A9W97_19125 | A9W97_05310 | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.893 |