Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OCB41377.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)    
Predicted Functional Partners:
OCB41376.1
Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.710
OCB34608.1
Secretion protein EspR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.695
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.694
OCB31495.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.671
OCB35453.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.644
OCB32295.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.617
OCB41375.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.611
OCB35220.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.559
OCB37707.1
Heparin-binding hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.558
OCB34925.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.545
Your Current Organism:
Mycobacterium malmoense
NCBI taxonomy Id: 1780
Other names: ATCC 29571, CCUG 37761, CIP 105775, DSM 44163, JCM 13391, M. malmoense, NCTC 11298
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.