Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OCB40849.1TIGR01777 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)    
Predicted Functional Partners:
OCB40850.1
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.871
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
     
 0.758
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  
  
 0.758
OCB40846.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.700
OCB40851.1
Short chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.544
OCB31855.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.488
A5676_06455
Hypothetical protein; Incomplete; too short partial abutting assembly gap; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.445
OCB34876.1
DtxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.422
OCB34943.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.422
OCB39330.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.414
Your Current Organism:
Mycobacterium malmoense
NCBI taxonomy Id: 1780
Other names: ATCC 29571, CCUG 37761, CIP 105775, DSM 44163, JCM 13391, M. malmoense, NCTC 11298
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.