node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OCB35812.1 | coaX | A5676_23265 | A5676_14935 | Nucleoside triphosphate hydrolase; Functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.714 |
OCB38730.1 | coaA | A5676_15165 | A5676_23980 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Type I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
OCB38730.1 | coaD | A5676_15165 | A5676_07850 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.974 |
OCB38730.1 | coaX | A5676_15165 | A5676_14935 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.879 |
OCB38730.1 | panC | A5676_15165 | A5676_14945 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.916 |
OCB38730.1 | panD | A5676_15165 | A5676_14940 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.494 |
OCB38730.1 | tmk | A5676_15165 | A5676_26010 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.569 |
OCB38808.1 | OCB38813.1 | A5676_14925 | A5676_14950 | Nucleoid-associated protein Lsr2; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.683 |
OCB38808.1 | coaX | A5676_14925 | A5676_14935 | Nucleoid-associated protein Lsr2; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.683 |
OCB38808.1 | lysS | A5676_14925 | A5676_14930 | Nucleoid-associated protein Lsr2; Derived by automated computational analysis using gene prediction method: Protein Homology. | lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.588 |
OCB38808.1 | panC | A5676_14925 | A5676_14945 | Nucleoid-associated protein Lsr2; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.683 |
OCB38808.1 | panD | A5676_14925 | A5676_14940 | Nucleoid-associated protein Lsr2; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.683 |
OCB38813.1 | OCB38808.1 | A5676_14950 | A5676_14925 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoid-associated protein Lsr2; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.683 |
OCB38813.1 | coaX | A5676_14950 | A5676_14935 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.943 |
OCB38813.1 | lysS | A5676_14950 | A5676_14930 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.870 |
OCB38813.1 | panC | A5676_14950 | A5676_14945 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.997 |
OCB38813.1 | panD | A5676_14950 | A5676_14940 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.928 |
coaA | OCB38730.1 | A5676_23980 | A5676_15165 | Type I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.926 |
coaA | coaD | A5676_23980 | A5676_07850 | Type I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.928 |
coaA | coaX | A5676_23980 | A5676_14935 | Type I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.904 |