| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| OCB38256.1 | OCB38749.1 | A5676_16015 | A5676_15125 | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.714 |
| OCB38256.1 | OCB41210.1 | A5676_16015 | A5676_09365 | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.812 |
| OCB38256.1 | carA | A5676_16015 | A5676_15130 | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. | 0.820 |
| OCB38256.1 | carB | A5676_16015 | A5676_15135 | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. | 0.834 |
| OCB38256.1 | pyrB | A5676_16015 | A5676_15115 | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.831 |
| OCB38256.1 | pyrC | A5676_16015 | A5676_15120 | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.839 |
| OCB38256.1 | pyrE | A5676_16015 | A5676_04025 | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.845 |
| OCB38256.1 | pyrF | A5676_16015 | A5676_15140 | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.830 |
| OCB38256.1 | pyrR | A5676_16015 | A5676_15110 | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.625 |
| OCB38749.1 | OCB38256.1 | A5676_15125 | A5676_16015 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.714 |
| OCB38749.1 | OCB41210.1 | A5676_15125 | A5676_09365 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.915 |
| OCB38749.1 | carA | A5676_15125 | A5676_15130 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. | 0.968 |
| OCB38749.1 | carB | A5676_15125 | A5676_15135 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. | 0.976 |
| OCB38749.1 | pyrB | A5676_15125 | A5676_15115 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.969 |
| OCB38749.1 | pyrC | A5676_15125 | A5676_15120 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.970 |
| OCB38749.1 | pyrD | A5676_15125 | A5676_09035 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Antitermination regulator; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.735 |
| OCB38749.1 | pyrE | A5676_15125 | A5676_04025 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.781 |
| OCB38749.1 | pyrF | A5676_15125 | A5676_15140 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.940 |
| OCB38749.1 | pyrR | A5676_15125 | A5676_15110 | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.941 |
| OCB41210.1 | OCB38256.1 | A5676_09365 | A5676_16015 | Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.812 |
