Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
OCB35185.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)    
Predicted Functional Partners:
OCB40435.1
Fused response regulator/thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.915
OCB33786.1
Anti-sigma regulatory factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.912
OCB36643.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.912
OCB35531.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.912
OCB39765.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.884
OCB36277.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.805
OCB34723.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.775
OCB34653.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.758
OCB36270.1
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.752
OCB40434.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.720
Your Current Organism:
Mycobacterium malmoense
NCBI taxonomy Id: 1780
Other names: ATCC 29571, CCUG 37761, CIP 105775, DSM 44163, JCM 13391, M. malmoense, NCTC 11298
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