Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A5676_26535Type VII secretion protein EsxI; Frameshifted; incomplete; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)    
Predicted Functional Partners:
OCB34547.1
Type VII secretion protein EccE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.887
OCB34548.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.878
OCB31405.1
Type VII secretion integral membrane protein EccD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.810
OCB37027.1
Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.769
OCB40445.1
Type VII secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.745
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
   
 0.745
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 0.744
OCB33503.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.733
OCB38417.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.733
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
   
 0.724
Your Current Organism:
Mycobacterium malmoense
NCBI taxonomy Id: 1780
Other names: ATCC 29571, CCUG 37761, CIP 105775, DSM 44163, JCM 13391, M. malmoense, NCTC 11298
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