WN55_00083 protein (Dufourea novaeangliae) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

WN55_00083

Dephospho-CoA kinase domain-containing protein. (235 aa)

Predicted Functional Partners:

WN55_05080

0.967

WN55_00660

0.876

WN55_05869

0.875

WN55_05647

0.874

WN55_11507

0.849

WN55_11254

0.829

WN55_05868

0.828

WN55_06128

0.823

WN55_05021

0.823

WN55_10142

0.816

Your Current Organism:

Dufourea novaeangliae

NCBI taxonomy Id: 178035
Other names: D. novaeangliae, Dufourea nova-angliae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WN55_00083	WN55_00660	A0A154NWD6	A0A154NY31	Dephospho-CoA kinase domain-containing protein.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.876
WN55_00083	WN55_05021	A0A154NWD6	A0A154PQS0	Dephospho-CoA kinase domain-containing protein.	V-type proton ATPase catalytic subunit A.	0.823
WN55_00083	WN55_05080	A0A154NWD6	A0A154PQJ6	Dephospho-CoA kinase domain-containing protein.	Pantothenate kinase 4.	0.967
WN55_00083	WN55_05647	A0A154NWD6	A0A154PNB5	Dephospho-CoA kinase domain-containing protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.874
WN55_00083	WN55_05868	A0A154NWD6	A0A154PMQ6	Dephospho-CoA kinase domain-containing protein.	Cytochrome c oxidase assembly protein COX19.	0.828
WN55_00083	WN55_05869	A0A154NWD6	A0A154PMS1	Dephospho-CoA kinase domain-containing protein.	Phosphopantothenoylcysteine decarboxylase.	0.875
WN55_00083	WN55_06128	A0A154NWD6	A0A154P289	Dephospho-CoA kinase domain-containing protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.823
WN55_00083	WN55_10142	A0A154NWD6	A0A154P322	Dephospho-CoA kinase domain-containing protein.	V-type proton ATPase subunit E.	0.816
WN55_00083	WN55_11254	A0A154NWD6	A0A154P9L0	Dephospho-CoA kinase domain-containing protein.	Heparanase.	0.829
WN55_00083	WN55_11507	A0A154NWD6	A0A154PC95	Dephospho-CoA kinase domain-containing protein.	Phosphopantothenate--cysteine ligase.	0.849
WN55_00660	WN55_00083	A0A154NY31	A0A154NWD6	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Dephospho-CoA kinase domain-containing protein.	0.876
WN55_00660	WN55_05647	A0A154NY31	A0A154PNB5	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.999
WN55_05021	WN55_00083	A0A154PQS0	A0A154NWD6	V-type proton ATPase catalytic subunit A.	Dephospho-CoA kinase domain-containing protein.	0.823
WN55_05021	WN55_06128	A0A154PQS0	A0A154P289	V-type proton ATPase catalytic subunit A.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.999
WN55_05021	WN55_10142	A0A154PQS0	A0A154P322	V-type proton ATPase catalytic subunit A.	V-type proton ATPase subunit E.	0.999
WN55_05021	WN55_11254	A0A154PQS0	A0A154P9L0	V-type proton ATPase catalytic subunit A.	Heparanase.	0.999
WN55_05080	WN55_00083	A0A154PQJ6	A0A154NWD6	Pantothenate kinase 4.	Dephospho-CoA kinase domain-containing protein.	0.967
WN55_05080	WN55_05868	A0A154PQJ6	A0A154PMQ6	Pantothenate kinase 4.	Cytochrome c oxidase assembly protein COX19.	0.966
WN55_05080	WN55_05869	A0A154PQJ6	A0A154PMS1	Pantothenate kinase 4.	Phosphopantothenoylcysteine decarboxylase.	0.966
WN55_05080	WN55_11507	A0A154PQJ6	A0A154PC95	Pantothenate kinase 4.	Phosphopantothenate--cysteine ligase.	0.966

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

36

average node degree:

6.55

avg. local clustering coefficient:

0.744

expected number of edges:

12

PPI enrichment p-value:

1.56e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140359

ABC-type transporter activity

5 of 77

1.82

2.18

1.40e-05

GO:0005524

ATP binding

6 of 823

0.87

0.56

0.0152

GO:0043168

Anion binding

7 of 1447

0.69

0.44

0.0216

GO:0043167

Ion binding

9 of 2805

0.51

0.35

0.0216

GO:0005488

Binding

11 of 4994

0.35

0.27

0.0216

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0071944

Cell periphery

6 of 826

0.87

0.47

0.0468

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15737

Type 1 protein exporter

4 of 5

2.91

3.74

1.31e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

5 of 162

1.49

1.66

4.79e-05

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9754706

Atorvastatin ADME

4 of 18

2.35

2.83

3.33e-06

MAP-159418

Recycling of bile acids and salts

4 of 18

2.35

2.83

3.33e-06

MAP-983170

Antigen Presentation: Folding, assembly and peptide loading of class I MHC

4 of 28

2.16

2.67

4.31e-06

MAP-382556

ABC-family proteins mediated transport

5 of 64

1.9

2.49

3.33e-06

MAP-9757110

Prednisone ADME

4 of 37

2.04

2.43

9.66e-06

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0067

ATP-binding

6 of 381

1.2

1.19

0.00017

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00664

ABC transporter transmembrane region

5 of 36

2.15

3.18

2.64e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039421

Type 1 protein exporter

5 of 12

2.63

4.31

6.13e-09

IPR036640

ABC transporter type 1, transmembrane domain superfamily

5 of 38

2.12

3.06

4.71e-07

IPR011527

ABC transporter type 1, transmembrane domain

5 of 38

2.12

3.06

4.71e-07

IPR017871

ABC transporter-like, conserved site

5 of 61

1.92

2.58

2.17e-06

IPR003439

ABC transporter-like, ATP-binding domain

5 of 70

1.86

2.45

3.33e-06

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

5 of 142

1.55

1.71

5.34e-05

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