STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WN55_071181-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1112 aa)    
Predicted Functional Partners:
WN55_05154
Multiple PDZ domain protein.
   
 0.994
WN55_01132
Diacylglycerol kinase.
   
 0.950
WN55_04733
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma.
    
 0.938
WN55_01813
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.938
WN55_06890
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 
 0.928
WN55_07862
Type I inositol 1,4,5-trisphosphate 5-phosphatase.
   
 
 0.928
WN55_05801
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
     
 0.925
WN55_08105
Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.
     
 0.923
WN55_01580
Diacylglycerol kinase.
     
 0.922
WN55_00432
Inositol polyphosphate 5-phosphatase K.
     
 0.922
Your Current Organism:
Dufourea novaeangliae
NCBI taxonomy Id: 178035
Other names: D. novaeangliae, Dufourea nova-angliae
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