WN55_01056 protein (Dufourea novaeangliae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:

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Cooccurrence

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[Homology]

Score

WN55_01056

Fat-like cadherin-related tumor suppressor like protein. (1243 aa)

Predicted Functional Partners:

WN55_05056

0.787

WN55_09231

0.766

WN55_07085

0.755

WN55_01060

0.746

WN55_03484

0.715

WN55_03631

0.703

WN55_05268

0.703

WN55_06145

0.657

WN55_01487

0.657

WN55_01484

0.657

Your Current Organism:

Dufourea novaeangliae

NCBI taxonomy Id: 178035
Other names: D. novaeangliae, Dufourea nova-angliae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WN55_01056	WN55_01060	A0A154PE04	A0A154PE32	Fat-like cadherin-related tumor suppressor like protein.	Protein expanded.	0.746
WN55_01056	WN55_01484	A0A154PE04	A0A154PGD4	Fat-like cadherin-related tumor suppressor like protein.	Neural-cadherin.	0.657
WN55_01056	WN55_01487	A0A154PE04	A0A154PEV6	Fat-like cadherin-related tumor suppressor like protein.	Neural-cadherin.	0.657
WN55_01056	WN55_03484	A0A154PE04	A0A154PJE4	Fat-like cadherin-related tumor suppressor like protein.	Neurogenic locus Notch protein.	0.715
WN55_01056	WN55_03631	A0A154PE04	A0A154PJX4	Fat-like cadherin-related tumor suppressor like protein.	Arginine-glutamic acid dipeptide repeats protein.	0.703
WN55_01056	WN55_05056	A0A154PE04	A0A154PNP7	Fat-like cadherin-related tumor suppressor like protein.	LIX1-like protein.	0.787
WN55_01056	WN55_05268	A0A154PE04	A0A154PP98	Fat-like cadherin-related tumor suppressor like protein.	Uncharacterized protein.	0.703
WN55_01056	WN55_06145	A0A154PE04	A0A154P4C2	Fat-like cadherin-related tumor suppressor like protein.	Cadherin-89D.	0.657
WN55_01056	WN55_07085	A0A154PE04	A0A154PS29	Fat-like cadherin-related tumor suppressor like protein.	Protein dachsous.	0.755
WN55_01056	WN55_09231	A0A154PE04	A0A154P905	Fat-like cadherin-related tumor suppressor like protein.	Casein kinase I isoform epsilon.	0.766
WN55_01060	WN55_01056	A0A154PE32	A0A154PE04	Protein expanded.	Fat-like cadherin-related tumor suppressor like protein.	0.746
WN55_01060	WN55_03484	A0A154PE32	A0A154PJE4	Protein expanded.	Neurogenic locus Notch protein.	0.561
WN55_01484	WN55_01056	A0A154PGD4	A0A154PE04	Neural-cadherin.	Fat-like cadherin-related tumor suppressor like protein.	0.657
WN55_01484	WN55_05056	A0A154PGD4	A0A154PNP7	Neural-cadherin.	LIX1-like protein.	0.533
WN55_01484	WN55_07085	A0A154PGD4	A0A154PS29	Neural-cadherin.	Protein dachsous.	0.444
WN55_01487	WN55_01056	A0A154PEV6	A0A154PE04	Neural-cadherin.	Fat-like cadherin-related tumor suppressor like protein.	0.657
WN55_01487	WN55_05056	A0A154PEV6	A0A154PNP7	Neural-cadherin.	LIX1-like protein.	0.533
WN55_03484	WN55_01056	A0A154PJE4	A0A154PE04	Neurogenic locus Notch protein.	Fat-like cadherin-related tumor suppressor like protein.	0.715
WN55_03484	WN55_01060	A0A154PJE4	A0A154PE32	Neurogenic locus Notch protein.	Protein expanded.	0.561
WN55_03631	WN55_01056	A0A154PJX4	A0A154PE04	Arginine-glutamic acid dipeptide repeats protein.	Fat-like cadherin-related tumor suppressor like protein.	0.703

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

30

average node degree:

5.45

avg. local clustering coefficient:

0.822

expected number of edges:

11

PPI enrichment p-value:

2.3e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050464

Nitrate reductase (NADPH) activity

2 of 2

2.91

1.31

0.0043

GO:0003735

Structural constituent of ribosome

5 of 152

1.42

1.21

0.0011

GO:0043546

Molybdopterin cofactor binding

2 of 5

2.51

1.2

0.0064

GO:0030151

Molybdenum ion binding

2 of 8

2.31

1.07

0.0107

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005763

Mitochondrial small ribosomal subunit

5 of 29

2.14

3.21

2.26e-07

GO:0005576

Extracellular region

4 of 293

1.04

0.61

0.0251

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4710

Organellar ribosome, and Plant-pathogen interaction

6 of 53

1.96

3.24

4.74e-08

CL:8987

Eukaryotic molybdopterin oxidoreductase, and Electron transport from NADPH to Ferredoxin

4 of 11

2.47

3.22

6.89e-07

CL:4769

Organellar small ribosomal subunit, and CTP metabolic process

4 of 14

2.36

3.04

1.23e-06

CL:8990

Oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor, and Eukaryotic molybdopterin oxidoreductase

3 of 5

2.69

2.67

1.15e-05

CL:4772

Organellar small ribosomal subunit, and Ribosomal protein S10

3 of 9

2.43

2.34

3.81e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

5 of 168

1.38

1.39

0.00017

map00910

Nitrogen metabolism

3 of 46

1.72

1.3

0.0019

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

5 of 252

1.21

0.83

0.0072

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005763

Mitochondrial small ribosomal subunit

4 of 26

2.09

2.24

3.26e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0274

FAD

3 of 63

1.59

0.89

0.0143

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03404

Mo-co oxidoreductase dimerisation domain

4 of 6

2.73

3.54

2.55e-07

PF00174

Oxidoreductase molybdopterin binding domain

4 of 7

2.66

3.52

2.55e-07

PF00970

Oxidoreductase FAD-binding domain

3 of 9

2.43

2.13

9.87e-05

PF00175

Oxidoreductase NAD-binding domain

3 of 16

2.18

1.81

0.00032

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR008335

Eukaryotic molybdopterin oxidoreductase

4 of 6

2.73

3.31

7.19e-07

IPR005066

Moybdenum cofactor oxidoreductase, dimerisation

4 of 6

2.73

3.31

7.19e-07

IPR000572

Oxidoreductase, molybdopterin-binding domain

4 of 6

2.73

3.31

7.19e-07

IPR036374

Oxidoreductase, molybdopterin-binding domain superfamily

4 of 7

2.66

3.29

7.19e-07

IPR014756

Immunoglobulin E-set

4 of 24

2.13

2.42

1.39e-05

(more ...)

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