WN55_00408 protein (Dufourea novaeangliae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

WN55_00408

Uncharacterized protein. (68 aa)

Predicted Functional Partners:

WN55_03367

0.633

WN55_06956

0.508

WN55_08301

0.493

WN55_06177

0.431

Your Current Organism:

Dufourea novaeangliae

NCBI taxonomy Id: 178035
Other names: D. novaeangliae, Dufourea nova-angliae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WN55_00408	WN55_03367	A0A154PFJ9	A0A154PMB9	Uncharacterized protein.	SH3 domain-containing RING finger protein 3.	0.633
WN55_00408	WN55_06177	A0A154PFJ9	A0A154P2E4	Uncharacterized protein.	26S proteasome non-ATPase regulatory subunit 4.	0.431
WN55_00408	WN55_06956	A0A154PFJ9	A0A154PRE5	Uncharacterized protein.	Rab GTPase-binding effector protein 1.	0.508
WN55_00408	WN55_08301	A0A154PFJ9	A0A154P8S1	Uncharacterized protein.	SAGA-associated factor 29 like protein.	0.493
WN55_03367	WN55_00408	A0A154PMB9	A0A154PFJ9	SH3 domain-containing RING finger protein 3.	Uncharacterized protein.	0.633
WN55_03367	WN55_06956	A0A154PMB9	A0A154PRE5	SH3 domain-containing RING finger protein 3.	Rab GTPase-binding effector protein 1.	0.616
WN55_03367	WN55_08301	A0A154PMB9	A0A154P8S1	SH3 domain-containing RING finger protein 3.	SAGA-associated factor 29 like protein.	0.579
WN55_06177	WN55_00408	A0A154P2E4	A0A154PFJ9	26S proteasome non-ATPase regulatory subunit 4.	Uncharacterized protein.	0.431
WN55_06956	WN55_00408	A0A154PRE5	A0A154PFJ9	Rab GTPase-binding effector protein 1.	Uncharacterized protein.	0.508
WN55_06956	WN55_03367	A0A154PRE5	A0A154PMB9	Rab GTPase-binding effector protein 1.	SH3 domain-containing RING finger protein 3.	0.616
WN55_06956	WN55_08301	A0A154PRE5	A0A154P8S1	Rab GTPase-binding effector protein 1.	SAGA-associated factor 29 like protein.	0.499
WN55_08301	WN55_00408	A0A154P8S1	A0A154PFJ9	SAGA-associated factor 29 like protein.	Uncharacterized protein.	0.493
WN55_08301	WN55_03367	A0A154P8S1	A0A154PMB9	SAGA-associated factor 29 like protein.	SH3 domain-containing RING finger protein 3.	0.579
WN55_08301	WN55_06956	A0A154P8S1	A0A154PRE5	SAGA-associated factor 29 like protein.	Rab GTPase-binding effector protein 1.	0.499

Network Stats

number of nodes:

8

number of edges:

11

average node degree:

2.75

avg. local clustering coefficient:

0.899

expected number of edges:

11

PPI enrichment p-value:

0.482

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045471

Response to ethanol

2 of 3

2.92

0.94

0.0198

GO:0006636

Unsaturated fatty acid biosynthetic process

2 of 7

2.55

0.86

0.0277

GO:0000001

Mitochondrion inheritance

2 of 8

2.5

0.86

0.0277

GO:0042128

Nitrate assimilation

2 of 9

2.45

0.85

0.0277

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050464

Nitrate reductase (NADPH) activity

2 of 2

3.1

1.26

0.0053

GO:0004768

stearoyl-CoA 9-desaturase activity

2 of 2

3.1

1.26

0.0053

GO:0043546

Molybdopterin cofactor binding

2 of 7

2.55

1.24

0.0053

GO:0030151

Molybdenum ion binding

2 of 11

2.36

1.17

0.0069

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:11839

Nitrate reductase activity

2 of 6

2.62

0.93

0.0209

CL:11412

Mixed, incl. Ribonucleoside-diphosphate reductase complex, and GDP metabolic process

2 of 6

2.62

0.93

0.0209

CL:10176

Acyl-CoA desaturase, and Fatty acid elongation

2 of 5

2.7

0.93

0.0209

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0349

Heme

4 of 61

1.92

2.11

3.44e-05

KW-0275

Fatty acid biosynthesis

2 of 12

2.32

1.35

0.0031

KW-0249

Electron transport

2 of 15

2.22

1.33

0.0031

KW-0560

Oxidoreductase

4 of 253

1.3

1.0

0.0028

KW-0479

Metal-binding

5 of 717

0.94

0.69

0.0047

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03404

Mo-co oxidoreductase dimerisation domain

2 of 3

2.92

1.21

0.0064

PF00174

Oxidoreductase molybdopterin binding domain

2 of 4

2.8

1.21

0.0064

PF00487

Fatty acid desaturase

2 of 13

2.29

0.9

0.0222

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001199

Cytochrome b5-like heme/steroid binding domain

4 of 38

2.12

2.09

7.36e-05

IPR036400

Cytochrome b5-like heme/steroid binding domain superfamily

4 of 40

2.1

2.08

7.36e-05

IPR018506

Cytochrome b5, heme-binding site

3 of 15

2.4

1.87

0.00031

IPR015876

Acyl-CoA desaturase

2 of 2

3.1

1.43

0.0026

IPR009160

Acyl-CoA desaturase, haem/steroid binding domain-containing

2 of 2

3.1

1.43

0.0026

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01117

Cytochrome b5-like Heme/Steroid binding domain

4 of 38

2.12

2.52

8.10e-06

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