WN55_02554 protein (Dufourea novaeangliae) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

WN55_02554

FAD synthase. (464 aa)

Predicted Functional Partners:

WN55_05295

0.972

WN55_00143

0.972

WN55_08793

0.952

WN55_03972

0.942

WN55_06408

0.925

WN55_00639

0.872

WN55_07698

0.828

WN55_00767

0.828

WN55_03236

0.828

WN55_08279

0.827

Your Current Organism:

Dufourea novaeangliae

NCBI taxonomy Id: 178035
Other names: D. novaeangliae, Dufourea nova-angliae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WN55_00143	WN55_00767	A0A154PCB6	A0A154PDZ1	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1.	Nitric oxide synthase; Produces nitric oxide (NO).	0.806
WN55_00143	WN55_02554	A0A154PCB6	A0A154PHK0	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1.	FAD synthase.	0.972
WN55_00143	WN55_03236	A0A154PCB6	A0A154PJZ3	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1.	NADPH-dependent diflavin oxidoreductase 1.	0.806
WN55_00143	WN55_03972	A0A154PCB6	A0A154PKQ8	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1.	Putative sulfite oxidase, mitochondrial.	0.961
WN55_00143	WN55_05295	A0A154PCB6	A0A154NXZ0	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1.	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase.	0.914
WN55_00143	WN55_06408	A0A154PCB6	A0A154P2J0	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1.	FAD synthase.	0.972
WN55_00143	WN55_07698	A0A154PCB6	A0A154P5Z1	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.806
WN55_00639	WN55_00767	A0A154NZP9	A0A154PDZ1	Cytochrome b5 reductase 4.	Nitric oxide synthase; Produces nitric oxide (NO).	0.939
WN55_00639	WN55_02554	A0A154NZP9	A0A154PHK0	Cytochrome b5 reductase 4.	FAD synthase.	0.872
WN55_00639	WN55_03236	A0A154NZP9	A0A154PJZ3	Cytochrome b5 reductase 4.	NADPH-dependent diflavin oxidoreductase 1.	0.939
WN55_00639	WN55_03972	A0A154NZP9	A0A154PKQ8	Cytochrome b5 reductase 4.	Putative sulfite oxidase, mitochondrial.	0.967
WN55_00639	WN55_06408	A0A154NZP9	A0A154P2J0	Cytochrome b5 reductase 4.	FAD synthase.	0.872
WN55_00639	WN55_07698	A0A154NZP9	A0A154P5Z1	Cytochrome b5 reductase 4.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.939
WN55_00639	WN55_08793	A0A154NZP9	A0A154NZT1	Cytochrome b5 reductase 4.	Riboflavin kinase.	0.747
WN55_00767	WN55_00143	A0A154PDZ1	A0A154PCB6	Nitric oxide synthase; Produces nitric oxide (NO).	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1.	0.806
WN55_00767	WN55_00639	A0A154PDZ1	A0A154NZP9	Nitric oxide synthase; Produces nitric oxide (NO).	Cytochrome b5 reductase 4.	0.939
WN55_00767	WN55_02554	A0A154PDZ1	A0A154PHK0	Nitric oxide synthase; Produces nitric oxide (NO).	FAD synthase.	0.828
WN55_00767	WN55_03972	A0A154PDZ1	A0A154PKQ8	Nitric oxide synthase; Produces nitric oxide (NO).	Putative sulfite oxidase, mitochondrial.	0.938
WN55_00767	WN55_05295	A0A154PDZ1	A0A154NXZ0	Nitric oxide synthase; Produces nitric oxide (NO).	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase.	0.806
WN55_00767	WN55_06408	A0A154PDZ1	A0A154P2J0	Nitric oxide synthase; Produces nitric oxide (NO).	FAD synthase.	0.828

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Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.83

expected number of edges:

15

PPI enrichment p-value:

0.0417

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 114

1.55

3.35

2.24e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 55

1.78

4.0

1.47e-12

GO:0019843

rRNA binding

7 of 42

1.78

3.3

2.02e-09

GO:0003723

RNA binding

8 of 121

1.38

2.08

2.56e-08

GO:0000049

tRNA binding

4 of 28

1.72

1.74

0.00013

GO:0003676

Nucleic acid binding

9 of 504

0.81

0.76

5.43e-05

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 63

1.72

3.82

8.73e-13

GO:0015935

Small ribosomal subunit

3 of 6

2.26

2.33

3.03e-05

GO:0005622

Intracellular anatomical structure

11 of 1355

0.47

0.41

0.00014

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:23342046

(2013) The genome sequences of Cellulomonas fimi and Cellvibrio gilvus reveal the cellulolytic strategies of two facultative anaerobes, transfer of Cellvibrio gilvus to the genus Cellulomonas, and proposal of Cellulomonas gilvus sp. nov.

3 of 32

1.53

0.95

0.0091

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:162

Ribosome

9 of 43

1.88

4.66

9.85e-14

CL:166

rRNA-binding

7 of 28

1.96

4.23

3.68e-11

CL:169

rRNA-binding

5 of 15

2.08

3.46

3.66e-08

CL:133

Translation, and Protein export

11 of 136

1.47

2.97

9.85e-14

CL:173

mRNA binding, and rRNA-binding

3 of 6

2.26

2.21

5.49e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

sde03010

Ribosome

9 of 53

1.79

4.26

1.58e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 52

1.69

2.92

9.28e-09

GOCC:0022626

Cytosolic ribosome

5 of 29

1.8

2.55

1.03e-06

GOCC:0044391

Ribosomal subunit

5 of 33

1.74

2.44

1.23e-06

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 13

1.92

1.77

0.00024

GOCC:0043229

Intracellular organelle

9 of 280

1.07

1.29

3.19e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 55

1.78

4.11

4.44e-13

KW-0699

rRNA-binding

7 of 39

1.82

3.57

3.82e-10

KW-0820

tRNA-binding

3 of 19

1.76

1.43

0.0010

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