STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WN55_03975Hydroxymethylglutaryl-CoA lyase, mitochondrial. (249 aa)    
Predicted Functional Partners:
WN55_06777
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.993
WN55_07718
Methylglutaconyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.975
WN55_00922
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.974
WN55_01166
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.962
WN55_01626
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.962
WN55_07047
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial.
  
 0.962
WN55_02310
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
    
 0.961
WN55_11205
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial.
 
 0.960
WN55_01711
Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.956
WN55_11456
Trifunctional enzyme subunit beta, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.954
Your Current Organism:
Dufourea novaeangliae
NCBI taxonomy Id: 178035
Other names: D. novaeangliae, Dufourea nova-angliae
Server load: low (20%) [HD]