STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WN55_04891Crossover junction endonuclease MUS81. (544 aa)    
Predicted Functional Partners:
WN55_07835
Crossover junction endonuclease EME1.
   
 0.993
WN55_07841
DNA excision repair protein ERCC-1.
   
 0.987
WN55_10384
Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Belongs to the RecA family.
   
 0.982
WN55_01153
DNA repair endonuclease XPF.
    
 0.964
WN55_09182
ATP-dependent DNA helicase Q4.
   
 0.957
WN55_10976
Bloom syndrome protein like protein.
   
 0.956
WN55_00395
Xylosyltransferase oxt.
   
 0.954
WN55_04428
Fanconi anemia group M protein like protein.
    
 0.949
WN55_04341
DNA repair protein complementing XP-A cells like protein.
    
 0.944
WN55_03698
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.939
Your Current Organism:
Dufourea novaeangliae
NCBI taxonomy Id: 178035
Other names: D. novaeangliae, Dufourea nova-angliae
Server load: low (28%) [HD]