STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmCD_223S rRNA (uracil-C(5))-methyltransferase RlmCD; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (464 aa)    
Predicted Functional Partners:
rlmL
Ribosomal RNA large subunit methyltransferase K/L.
  
  
 0.772
CVI70972.1
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.754
CVI70975.1
Hypothetical protein; Putative metallophosphoesterase MG207 homolog.
       0.747
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.663
CVI70969.1
Molybdopterin biosynthesis protein MoeB.
       0.475
CVI70978.1
HTH domain protein.
       0.460
CVI70980.1
Hypothetical protein.
       0.460
rsmI
Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
  
 0.423
pheT
Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
    0.408
rsmF_1
Ribosomal RNA small subunit methyltransferase F.
 
  
 0.407
Your Current Organism:
Eubacteriaceae bacterium CHKCI004
NCBI taxonomy Id: 1780380
Other names: E. bacterium CHKCI004
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.