STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gutBSorbitol dehydrogenase. (419 aa)    
Predicted Functional Partners:
nifJ
Pyruvate-flavodoxin oxidoreductase.
    
 0.932
mtlA
PTS system mannitol-specific EIICBA component.
 
  
 0.905
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
  0.894
manX
PTS system mannose-specific EIIAB component.
  
 
 0.862
fruA
PTS system fructose-specific EIIABC component.
  
 
 0.857
bglF
PTS system beta-glucoside-specific EIIBCA component.
  
 
 0.847
ptsG
PTS system glucose-specific EIICBA component.
  
 
 0.847
fabG_1
3-oxoacyl-[acyl-carrier-protein] reductase FabG; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.813
fabG_2
3-oxoacyl-[acyl-carrier-protein] reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.813
tdcB
L-threonine dehydratase catabolic TdcB.
   
 0.811
Your Current Organism:
Eubacteriaceae bacterium CHKCI004
NCBI taxonomy Id: 1780380
Other names: E. bacterium CHKCI004
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.