Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORW22080.123S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (391 aa)    
Predicted Functional Partners:
ORW22079.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.841
rsmI
16S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
  
 0.630
ORW16306.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.615
ORW22078.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.612
ORW16208.1
SAM-dependent methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
   
  
 0.589
ORW22077.1
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.586
nnrD
Bifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-spec [...]
 
  
 0.561
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.536
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
  
 0.533
ORW23024.1
rRNA cytosine-C5-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
  
 0.520
Your Current Organism:
Mycolicibacter nonchromogenicus
NCBI taxonomy Id: 1782
Other names: ATCC 19530, CCUG 28009, CIP 106811, DSM 44164, JCM 6364, M. nonchromogenicus, Mycobacterium nonchromogenicum, NCTC 10424
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