Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
ORB75131.1Phosphotyrosine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)    
Predicted Functional Partners:
ORB73296.1
NADH-quinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.896
ORB75217.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.889
ORB75216.1
DUF4440 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.752
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.741
ORB74800.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.734
ORB72424.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.734
ORB75999.1
Sodium-independent anion transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.727
nuoB
NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
    
   0.710
ORB62314.1
Cutinase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.702
ORB74166.1
Cutinase family protein; Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.
  
 
 
 0.701
Your Current Organism:
Mycobacterium scrofulaceum
NCBI taxonomy Id: 1783
Other names: ATCC 19981, CCUG 29045, CIP 105416, DSM 43992, JCM 6381, M. scrofulaceum, NCTC 10803
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