STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORB74636.1Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)    
Predicted Functional Partners:
egtB
iron(II)-dependent oxidoreductase EgtB; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
  
 
 0.891
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
       0.794
ORB74635.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.743
ORB72193.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.592
ORB74923.1
Sulfatase-modifying factor 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.579
ORB70154.1
GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.533
ORB73979.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.510
ddl
D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
    
  0.497
ORB70591.1
Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.459
ORB74012.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.446
Your Current Organism:
Mycobacterium scrofulaceum
NCBI taxonomy Id: 1783
Other names: ATCC 19981, CCUG 29045, CIP 105416, DSM 43992, JCM 6381, M. scrofulaceum, NCTC 10803
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