Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ORB74557.1Dolichyl-phosphate-mannose--protein mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)    
Predicted Functional Partners:
rsmI
16S rRNA (cytidine(1402)-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.767
BST44_25440
Hypothetical protein; Internal stop; incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.733
ORB76045.1
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.680
ORB75803.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.677
ORB72593.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.672
ORB71949.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.669
ORB71050.1
Primosomal protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.655
ORB74676.1
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.651
ORB75784.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.646
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
 
 0.638
Your Current Organism:
Mycobacterium scrofulaceum
NCBI taxonomy Id: 1783
Other names: ATCC 19981, CCUG 29045, CIP 105416, DSM 43992, JCM 6381, M. scrofulaceum, NCTC 10803
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