Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ORB74371.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)    
Predicted Functional Partners:
ORB74370.1
Alpha-ketoacid dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.998
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.997
ORB73958.1
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
ORB73916.1
Alpha-ketoacid dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.982
ORB76118.1
Alpha-ketoacid dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.977
ORB72587.1
Alpha-ketoacid dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.977
ORB74372.1
Phosphopantetheine-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.971
ORB71877.1
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.966
ORB74368.1
acetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.965
ORB75504.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.955
Your Current Organism:
Mycobacterium scrofulaceum
NCBI taxonomy Id: 1783
Other names: ATCC 19981, CCUG 29045, CIP 105416, DSM 43992, JCM 6381, M. scrofulaceum, NCTC 10803
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