ORB74463.1 protein (Mycobacterium scrofulaceum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Mycobacterium scrofulaceum

NCBI taxonomy Id: 1783
Other names: ATCC 19981, CCUG 29045, CIP 105416, DSM 43992, JCM 6381, M. scrofulaceum, NCTC 10803

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... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ORB69221.1	ORB70892.1	BST44_25885	BST44_22425	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.775
ORB69221.1	ORB74463.1	BST44_25885	BST44_09680	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.775
ORB69221.1	ORB74584.1	BST44_25885	BST44_09385	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.	Peptidase S1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.775
ORB69221.1	ORB75178.1	BST44_25885	BST44_06270	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.775
ORB69221.1	glpK	BST44_25885	BST44_08070	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.882
ORB70892.1	ORB69221.1	BST44_22425	BST44_25885	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.	0.775
ORB70892.1	ORB74463.1	BST44_22425	BST44_09680	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.859
ORB70892.1	ORB74584.1	BST44_22425	BST44_09385	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidase S1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.658
ORB70892.1	ORB75178.1	BST44_22425	BST44_06270	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.810
ORB70892.1	arc	BST44_22425	BST44_13630	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.775
ORB70892.1	glpK	BST44_22425	BST44_08070	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.794
ORB70892.1	rplD	BST44_22425	BST44_07880	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.635
ORB70892.1	rplY	BST44_22425	BST44_09035	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.	0.657
ORB70892.1	rpsF	BST44_22425	BST44_17980	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.650
ORB74382.1	ORB74463.1	BST44_09685	BST44_09680	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.732
ORB74463.1	ORB69221.1	BST44_09680	BST44_25885	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family.	0.775
ORB74463.1	ORB70892.1	BST44_09680	BST44_22425	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.859
ORB74463.1	ORB74382.1	BST44_09680	BST44_09685	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.732
ORB74463.1	ORB74584.1	BST44_09680	BST44_09385	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidase S1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.734
ORB74463.1	ORB75178.1	BST44_09680	BST44_06270	Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.712