Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ORB72147.1Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)    
Predicted Functional Partners:
ORB72176.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.646
ORB72148.1
ATPase/protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.634
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.536
ORB69893.1
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.513
ORB72149.1
methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.503
ORB72150.1
methylmalonyl-CoA mutase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.503
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.483
ORB75209.1
Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.479
ORB74587.1
Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.453
ORB71431.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.432
Your Current Organism:
Mycobacterium scrofulaceum
NCBI taxonomy Id: 1783
Other names: ATCC 19981, CCUG 29045, CIP 105416, DSM 43992, JCM 6381, M. scrofulaceum, NCTC 10803
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