Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE0019Conserved hypothetical protein. (297 aa)    
Predicted Functional Partners:
PAE0020
Binding protein, putative; Transport and binding proteins; Anions.
 
     0.873
PAE0022
Sulfate transport system, permease protein, putative; Transport and binding proteins; Anions.
 
    0.867
PAE0727
Molybdenum cofactor biosynthesis protein D/E; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
     
 0.707
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.635
PAE0622
Aldehyde ferredoxin oxidoreductase (aor); Energy metabolism; Fermentation.
 
     0.583
PAE2052
Aldehyde ferredoxin oxidoreductase (aor); Energy metabolism; Fermentation.
 
     0.583
PAE3427
Aldehyde ferredoxin oxidoreductase (aor); Energy metabolism; Fermentation.
 
     0.568
PAE0023
Sulfate transport system, ATP-binding protein, putative; Transport and binding proteins; Anions.
       0.564
PAE2664
Formate dehydrogenase delta subunit; Energy metabolism; Electron transport.
 
   
 0.514
PAE3453
Molybdopterin-guanine dinucleotide biosynthesis protein A; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
  
  
 0.483
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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