Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE0020Binding protein, putative; Transport and binding proteins; Anions. (313 aa)    
Predicted Functional Partners:
PAE0022
Sulfate transport system, permease protein, putative; Transport and binding proteins; Anions.
 
  
 0.996
PAE0023
Sulfate transport system, ATP-binding protein, putative; Transport and binding proteins; Anions.
    
  0.956
PAE0019
Conserved hypothetical protein.
 
     0.873
PAE0622
Aldehyde ferredoxin oxidoreductase (aor); Energy metabolism; Fermentation.
 
   
 0.635
PAE2052
Aldehyde ferredoxin oxidoreductase (aor); Energy metabolism; Fermentation.
 
   
 0.627
PAE3427
Aldehyde ferredoxin oxidoreductase (aor); Energy metabolism; Fermentation.
 
   
 0.610
PAE2826
Polyferredoxin; Energy metabolism; Electron transport.
  
     0.567
PAE2664
Formate dehydrogenase delta subunit; Energy metabolism; Electron transport.
 
     0.552
PAE0813
Molybdenum-pterin-binding protein, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
       0.470
PAE3465
Molybdenum cofactor biosynthesis protein (moaA); Biosynthesis of cofactors, prosthetic groups, and carriers; Molybdopterin.
 
   
 0.446
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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