Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE0039Conserved hypothetical protein. (375 aa)    
Predicted Functional Partners:
PAE2785
ABC transporter ATP-binding protein, putative; Transport and binding proteins; Unknown substrate.
 
 
 0.835
PAE2286
ABC transporter ATP-binding protein, putative; Transport and binding proteins; Unknown substrate.
 
 
 0.790
PAE0040
Hypothetical; Conserved within genome.
       0.785
PAE0041
Hypothetical protein.
       0.773
PAE2699
Iron (III) ABC transporter ATP-binding protein, putative; Transport and binding proteins; Cations.
 
 
 0.749
PAE2288
Conserved hypothetical protein.
  
     0.737
PAE0042
Egghead homolog; Unclassified.
       0.554
PAE0036
Conserved hypothetical protein.
       0.415
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
       0.409
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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