Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE0128Conserved hypothetical protein. (535 aa)    
Predicted Functional Partners:
PAE0122
Hypothetical protein.
     
 0.792
PAE0129
Conserved hypothetical protein.
       0.773
PAE2902
Hypothetical protein.
   
 
 0.735
PAE0131
Hypothetical protein.
       0.554
PAE0126
Conserved hypothetical protein.
       0.542
PAE0124
Hypothetical protein.
       0.523
PAE2839
Molybdopterin oxidoreductase, molybdopterin binding subunit part 2, authentic frameshift; Energy metabolism; Electron transport.
  
     0.518
PAE3429
Glycogen synthase (starch (bacterial glycogen) synthase), putative; Energy metabolism; Biosynthesis and degradation of polysaccharides.
 
     0.500
PAE1270
Conserved hypothetical protein.
 
     0.491
PAE3631
NAD dependent epimerase/dehydratase, putative; Purines, pyrimidines, nucleosides, and nucleotides; Sugar-nucleotide biosynthesis and conversions.
  
     0.476
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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