Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE0153Hypothetical protein. (303 aa)    
Predicted Functional Partners:
PAE0154
Hypothetical protein.
       0.791
vapC3
Conserved hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Has ribonuclease activity; Belongs to the PINc/VapC protein family.
 
     0.698
vAPb3
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.588
PAE0419
Glycosyl transferase, putative; Unclassified.
  
 
 0.538
PAE1584
Hypothetical; Conserved within genome.
  
 
 0.538
PAE1839
Glycosyl transferase, putative; Unclassified.
  
 
 0.538
PAE2355
Glycosyl transferase; Unclassified.
  
 
 0.538
srp54
Signal recognition particle (srp54 family), putative; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
    0.498
PAE0165
Conserved hypothetical protein.
 
     0.475
PAE0157
Hypothetical protein.
       0.471
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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