STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE0170Conserved protein (tenA homolog); Unclassified. (212 aa)    
Predicted Functional Partners:
PAE2535
Phosphomethylpyrimidine kinase; Biosynthesis of cofactors, prosthetic groups, and carriers; Thiamine.
 
 
 0.998
PAE1056
thiF/moeB/hesA family protein; Unclassified.
  
  
 0.805
PAE0171
Conserved hypothetical protein.
       0.791
thiC
Thiamine biosynthesis protein (thiC); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.732
PAE0172
Conserved hypothetical protein.
       0.604
PAE0167
Hypothetical protein.
       0.558
PAE0168
Conserved hypothetical protein.
       0.558
PAE2464
ABC transporter ATP-binding component; Transport and binding proteins; Amino acids, peptides and amines.
     
 0.539
PAE2529
Conserved hypothetical protein.
 
     0.457
PAE1543
Conserved hypothetical protein.
 
  
 0.416
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.