STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAE0315ABC-2 type transport system ATP-binding protein; Transport and binding proteins; Unknown substrate. (296 aa)    
Predicted Functional Partners:
PAE0316
ABC-2 type transport system, membrane protein; Transport and binding proteins; Unknown substrate.
  
  
 0.912
PAE0270
Transport and binding proteins; Unknown substrate.
 
  
 0.767
PAE1361
Hypothetical protein.
  
 
 0.681
PAE1362
nosD homolog; Energy metabolism; Electron transport.
  
 
 0.669
PAE1878
ATP binding protein, degenerate; Transport and binding proteins; Unknown substrate.
  
 0.620
PAE2301
ABC transporter ATP-binding component, degenerate; Transport and binding proteins; Unknown substrate.
  
 0.620
PAE3065
ABC-2 type transport system, membrane protein; Transport and binding proteins; Unknown substrate.
  
  
 0.520
rpl2
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
 
   0.497
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
 
  
 0.473
PAE2532
Ribose ABC transporter, ATP-binding protein, putative; Transport and binding proteins; Carbohydrates, organic alcohols, and acids.
 
  
 0.460
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.