Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAE0318Hypothetical protein. (538 aa)    
Predicted Functional Partners:
PAE0556
Amino acid permease; Transport and binding proteins; Amino acids, peptides and amines.
  
 0.961
PAE3429
Glycogen synthase (starch (bacterial glycogen) synthase), putative; Energy metabolism; Biosynthesis and degradation of polysaccharides.
 
  
 0.844
PAE3455
Maltose ABC transporter, maltose binding protein; Transport and binding proteins; Carbohydrates, organic alcohols, and acids.
 
  
 0.820
pyrC
Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.806
PAE0320
P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome.
       0.789
PAE3422
Conserved hypothetical protein.
 
 
 0.752
PAE1968
Alpha-glucosidase; Energy metabolism; Sugars; Belongs to the glycosyl hydrolase 31 family.
 
  
 0.716
PAE1185
Galactokinase; Energy metabolism; Sugars.
 
  
 0.701
PAE3457
Maltose ABC transporter, permease protein; Transport and binding proteins; Carbohydrates, organic alcohols, and acids.
 
  
 0.686
PAE1209
4-alpha-glucanotransferase (malQ); Energy metabolism; Biosynthesis and degradation of polysaccharides.
 
  
 0.677
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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