| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PAE0317 | PAE0318 | PAE0317 | PAE0318 | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | Hypothetical protein. | 0.576 |
| PAE0317 | PAE0320 | PAE0317 | PAE0320 | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | 0.575 |
| PAE0317 | pyrC | PAE0317 | PAE0322 | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.583 |
| PAE0318 | PAE0317 | PAE0318 | PAE0317 | Hypothetical protein. | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | 0.576 |
| PAE0318 | PAE0320 | PAE0318 | PAE0320 | Hypothetical protein. | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | 0.789 |
| PAE0318 | pyrC | PAE0318 | PAE0322 | Hypothetical protein. | Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.806 |
| PAE0320 | PAE0317 | PAE0320 | PAE0317 | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | 0.575 |
| PAE0320 | PAE0318 | PAE0320 | PAE0318 | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | Hypothetical protein. | 0.789 |
| PAE0320 | PAE0729 | PAE0320 | PAE0729 | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | Conserved hypothetical protein. | 0.727 |
| PAE0320 | PAE1156 | PAE0320 | PAE1156 | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | Conserved hypothetical protein. | 0.488 |
| PAE0320 | PAE3143 | PAE0320 | PAE3143 | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | Conserved hypothetical protein; Belongs to the UPF0273 family. | 0.685 |
| PAE0320 | PAE3364 | PAE0320 | PAE3364 | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | Conserved hypothetical protein. | 0.728 |
| PAE0320 | pyrC | PAE0320 | PAE0322 | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.792 |
| PAE0729 | PAE0320 | PAE0729 | PAE0320 | Conserved hypothetical protein. | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | 0.727 |
| PAE1156 | PAE0320 | PAE1156 | PAE0320 | Conserved hypothetical protein. | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | 0.488 |
| PAE3143 | PAE0320 | PAE3143 | PAE0320 | Conserved hypothetical protein; Belongs to the UPF0273 family. | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | 0.685 |
| PAE3364 | PAE0320 | PAE3364 | PAE0320 | Conserved hypothetical protein. | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | 0.728 |
| pyrC | PAE0317 | PAE0322 | PAE0317 | Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | GTP cyclohydrolase I, conjectural; Biosynthesis of cofactors, prosthetic groups, and carriers; Folic acid. | 0.583 |
| pyrC | PAE0318 | PAE0322 | PAE0318 | Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Hypothetical protein. | 0.806 |
| pyrC | PAE0320 | PAE0322 | PAE0320 | Dihydroorotase (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | P. aerophilum family 417, putative ATP binding; Hypothetical; Conserved within genome. | 0.792 |