Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAE0568Cation efflux system protein, conjectural; Transport and binding proteins; Cations. (319 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
    0.855
trpC
Indole-3-glycerol-phosphate synthase; Amino acid biosynthesis; Aromatic amino acid family; Belongs to the TrpC family.
  
  
 0.787
PAE0573
Conserved hypothetical protein.
       0.572
PAE2758
Cation-transporting ATPase (P-type); Transport and binding proteins; Cations.
 
 
 0.546
PAE2715
Transport and binding proteins; Cations.
 
 
0.460
PAE1703
Hypothetical protein.
  
    0.456
PAE1888
Multicopper oxidase; Unclassified.
 
 
 0.454
Your Current Organism:
Pyrobaculum aerophilum
NCBI taxonomy Id: 178306
Other names: P. aerophilum str. IM2, Pyrobaculum aerophilum IM2, Pyrobaculum aerophilum str. IM2, Pyrobaculum aerophilum strain IM2
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